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Properties

Sample
Organ/System
18 Common Properties
 Project
4DN
 Lab
Chuck Murry, UW
 Experiment Category
Sequencing
 Experiment Type
DNase Hi-C
 Organism
Human
 Sample Type
induced pluripotent stem cells
 Sample Tier
Unclassified
 Sample Category
Human stem cell
 Tissue Source
cardiac muscle cell
 Publication
Bertero A et al. (2019) PMID:31395619
 Modifications
No value
 Treatments
No value
 Assay Details
Enzyme: DNaseI
 Center
NOFIC - Shendure
 Status
Released
 Commendations
No value
 Warnings
Biosample Metadata Incomplete
 Validation Errors
No value
Title
Experiment Type
Biosample
Dataset
Condition
Assay Details
Lab
DNase Hi-C
LMNA-R225X-het with LMNA-R225X corrected to wild-type by Crispr differentiated to cardiac muscle cell
Hi-C on lamin A/C haploinsufficient hiPSC-derived cardiomyocytes
CRISPR corrected LMNA het R225X mutation to R225R - Clone 38
Enzyme
DNaseI
DNase Hi-C
LMNA-R225X-het with LMNA-R225X corrected to wild-type by Crispr differentiated to cardiac muscle cell
Hi-C on lamin A/C haploinsufficient hiPSC-derived cardiomyocytes
CRISPR corrected LMNA het R225X mutation to R225R - Clone 15
Enzyme
DNaseI
DNase Hi-C
LMNA-R225X-het differentiated to cardiac muscle cell
Hi-C on lamin A/C haploinsufficient hiPSC-derived cardiomyocytes
Heterozygous LMNA nonsense mutation R225X
Enzyme
DNaseI
- fin -